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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
16.97
Human Site:
S1224
Identified Species:
31.11
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
S1224
K
P
Q
E
P
P
I
S
L
L
L
L
L
Q
N
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
D1200
K
E
S
E
K
L
S
D
D
L
I
L
L
L
Q
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
S1224
K
P
Q
E
P
P
I
S
L
L
L
L
L
Q
N
Dog
Lupus familis
XP_534693
2280
250152
S1293
K
S
Q
E
P
P
I
S
L
L
L
L
L
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
S1223
K
A
P
E
P
P
V
S
L
L
L
L
L
Q
N
Rat
Rattus norvegicus
NP_001101807
1374
149708
H423
Y
I
S
S
S
S
R
H
A
L
P
C
V
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
D1183
K
E
P
E
K
L
P
D
E
L
I
L
L
L
Q
Chicken
Gallus gallus
XP_415317
2195
241321
S1203
R
T
Q
E
P
P
M
S
L
L
L
L
L
Q
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
A1135
I
M
G
R
G
S
D
A
A
R
E
I
E
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
A1629
G
P
G
E
T
S
S
A
L
D
K
I
G
A
G
Honey Bee
Apis mellifera
XP_393643
1982
216109
A1031
K
A
S
L
V
A
V
A
C
G
G
G
K
P
S
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
D1703
R
N
L
A
I
A
V
D
L
G
N
D
V
T
V
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
V176
A
E
K
D
G
K
E
V
S
R
T
A
K
C
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
33.3
100
93.3
N.A.
80
6.6
N.A.
33.3
80
N.A.
0
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
40
100
93.3
N.A.
86.6
13.3
N.A.
40
93.3
N.A.
26.6
N.A.
33.3
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
0
16
0
24
16
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% C
% Asp:
0
0
0
8
0
0
8
24
8
8
0
8
0
0
0
% D
% Glu:
0
24
0
62
0
0
8
0
8
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
0
16
0
0
0
0
16
8
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
8
0
24
0
0
0
16
16
0
0
0
% I
% Lys:
54
0
8
0
16
8
0
0
0
0
8
0
16
8
0
% K
% Leu:
0
0
8
8
0
16
0
0
54
62
39
54
54
16
0
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
39
% N
% Pro:
0
24
16
0
39
39
8
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
31
0
0
0
0
0
0
0
0
0
0
39
16
% Q
% Arg:
16
0
0
8
0
0
8
0
0
16
0
0
0
0
0
% R
% Ser:
0
8
24
8
8
24
16
39
8
0
0
0
0
8
8
% S
% Thr:
0
8
0
0
8
0
0
0
0
0
8
0
0
8
0
% T
% Val:
0
0
0
0
8
0
24
8
0
0
0
0
16
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _